
NAPROXEN PLUS
Naproxen BP + Esomeprazole
(as Esomeprazole Magnesium Trihydrate BP)




NAPROXEN PLUS
Naproxen BP + Esomeprazole
(as Esomeprazole Magnesium Trihydrate BP)





Naproxen Plus 500+20
Naproxen BP 500 mg + Esomeprazole 20 mg
(as Esomeprazole Magnesium Trihydrate BP)


Indications
Naproxen Plus tablet is indicated for the relief of signs & symptoms of-
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis &
To decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.
This consists of an immediate release Esomeprazole Magnesium layer & an enteric-coated Naproxen core. As a result, Esomeprazole is released first into the stomach, prior to the dissolution of Naproxen in the small intestine.
Naproxen is a NSAID with analgesic & antipyretic properties. The mechanism of action of Naproxen is to inhibit the prostaglandin synthesis. Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/k+ -ATPase in the gastric parietal cell by acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

Naproxen Plus 375+20
Naproxen BP 375 mg + Esomeprazole 20 mg
(as Esomeprazole Magnesium Trihydrate BP)


Indications
Naproxen Plus tablet is indicated for the relief of signs & symptoms of-
Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis &
To decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.
This consists of an immediate release Esomeprazole Magnesium layer & an enteric-coated Naproxen core. As a result, Esomeprazole is released first into the stomach, prior to the dissolution of Naproxen in the small intestine.
Naproxen is a NSAID with analgesic & antipyretic properties. The mechanism of action of Naproxen is to inhibit the prostaglandin synthesis. Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/k+ -ATPase in the gastric parietal cell by acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.
